Aberystwyth University are seeking to recruit a 1-year MPhil to work on a project entitled:
Effects of Rumen Bacterial Lipases on Ruminal Lipid Metabolism
Annual death rates from cardiovascular disease (CHD) are in the region of 100,000 (approx. 16% of deaths in total are due to CHD). Beef and milk are an important part of Westernised diets and as such it is imperative that their n-3 fatty acid content are increased and saturated fatty acids decreased in order to reduce the incidence of CHD. This research project, in partnership with Hybu Cig Cymru-Meat Promotion Wales, will further our understanding of rumen lipid metabolism and the potential for manipulation of lipolysis as a control point to enhance the healthiness of ruminant products.
The successful student will investigate:
1. The level of PUFA required to inhibit biohydrogenation in the presence of rumen fluid.
2. An evaluation of whether levels found in 1 can be achieved through enhancement of lipolysis using addition on phospholipases.
3. If levels of PUFA required to inhibit biohydrogenation can in theory be reached in vitro experimentation to try and achieve these levels using our rumen metagenomic lipases and a commercial lipase will be carried out.
4. If levels of PUFA required to inhibit biohydrogenation cannot in theory be achieved then attempts to manipulate lipolysis will focus on inhibition of the process.
The project will involve in vitro culturing techniques, thin layer chromatography, GC fatty acid analysis and microbial profiling techniques, such as terminal restriction fragment length polymorphism (T-RFLP).
The prospective applicant should have a minimum of a 1st or good 2:1 in a relevant degree, and be available to take up the studentship by 1 May 2013. The prospective applicant should also not hold or currently be working towards a qualification at Master’s Degree level or higher. The project is part-funded by the European Social Fund (ESF) through the European Union’s Convergence programme administered by the Welsh Government. KESS scholarships are collaborative awards with external partners. (Applicants need only apply, they do not need to search for partners.)
To apply, please submit the following to the Postgraduate Admissions Office (address below) by 28 March 2013.
1. A completed Research Programme Application Form, two references. Application and reference forms may be downloaded from http://www.aber.ac.uk/en/postgrad/howtoapply/.
2. A completed KESS application form (put the reference number AU50003 in the top right hand box of the application form) and an up-to-date CV. KESS application forms are available to download at the link below.
3. A Personal Statement of up to 1,000 words where you expand on your experience and interests and describe why you are a good candidate for this research studentship. Please refer to the Project Description.
Value of Award: A stipend of £10,130. Each scholarship has an additional budget for travel, equipment/consumables and training to support your research. KESS Scholarship holders do not pay fees.
Length: Full-time for 1 year. (Theses must be submitted 3 months after the funded one year study period.)
Training: The achievement of a Postgraduate Skills Development Award (PSDA) is compulsory for each KESS scholar (The PSDA is based on a 30 credit award, which is an additional award to the MPhil).
Eligibility: To be eligible to apply for a KESS award, you must be resident, upon application, in the Convergence Area of Wales and you must be able to take paid employment in the Convergence area on completion of the scholarship.
The Convergence Area means the following counties of Wales: Blaenau Gwent
Isle of Anglesey
Neath Port Talbot
Rhondda Cynon Taff
For further student eligibility criteria related to the individual projects, please view the details of the individual project above.
Informal enquiries should be made to Dr Sharon Huws at firstname.lastname@example.org or via 01970 623202.
Address for applications:
Postgraduate Admissions Office Recruitment & Admissions Student Welcome Centre Aberystwyth University Aberystwyth SY23 3FB
Quote Reference: AU50003
Closing date for applications: 28 March 2013Back to news listing